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cadmium and cadmium compounds iarc

CADMIUM AND CADMIUM COMPOUNDS IARC

CADMIUM AND CADMIUM COMPOUNDS Cadmium and cadmium compounds were considered by previous IARC Working Groups in 1972, 1975, 1987, and 1993 (IARC, 1973, 1976, 1987, 1993a). Since that time, new data have become available, these have been incorporated in the Monograph, and taken into consideration in the present evaluation. 1. Exposure Data

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Cadmium and Cadmium Compounds (IARC Summary & Evaluation

International Agency for Research on Cancer (IARC) Summaries & Evaluations CADMIUM AND CADMIUM COMPOUNDS (Group 1) For definition of Groups, see Preamble Evaluation.. VOL.: 58 (1993) (p. 119) CAS No.: 7440-43-9 Chem. Abstr.

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CADMIUM AND CADMIUM COMPOUNDS publications.iarc

Cadmium compounds did not produce dominant lethal effects in mice or rats nor did they increase the frequencies of chromos omal aberrations or micronuclei in mice treated in vivo. Cadmium compounds induced aneuploidy in hamsters but not in mice treated in vivo. They did not induce sis ter chromatid exchanges in human cells in vitro, and studies of

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Cadmium and Cadmium Compounds monographs.iarc

Cadmium and Cadmium Compounds. References to Supplementary Web Tables, Section 2. Elinder CG, Kjellström T, Hogstedt C et al. (1985). Cancer mortality of cadmium workers. Br J Ind Med, 42:651–655. PMID:4041382. Holden H (1980) Further mortality studies on workers exposed to cadmium fume. In: Proceedings of the

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CiteSeerX — CADMIUM AND CADMIUM COMPOUNDS Cadmium

Selected chemical and physical properties of cadmium compounds are presented in the previous IARC Monograph (IARC, 1993a). 1.3 Use of the agents Cadmium metal has specific properties that make it suitable for a wide variety of industrial applications.

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Cadmium and Cadmium Compounds MT CAS No. 7440-43-9

ous soluble and insoluble cadmium compounds caused tumors (sar-coma) at the injection site (IARC 1993, Waalkes and Rehm 1994a). Subcutaneous injection of cadmium compounds caused tumors at various tissue sites, including prostate tumors in rats, testicular tu-mors in rats and mice, lymphoma in mice, adrenal-gland tumors in

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eADMIUM AN eADMIUM COMPOUNDS monographs.iarc

Table 2. Physical and chemical properties or cadmium and cadmium compounds Chemical name Relative Melting-point Typical physical description Density Solubility atomic/ (0C) (g/cm3) molecular mass Cadmium metal 112.41 320.9 Silver-white, blue-tinged 8.642 Soluble in ammonium nitrate, dilute nitric acid, malleable metal hot sulfuric acid; insoluble in water Cadmium acetate 230.50 256 Colourless

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eADMIUM AN eADMIUM COMPOUNDS IARC Monographs

Table 2. Physical and chemical properties or cadmium and cadmium compounds Chemical name Relative Melting-point Typical physical description Density Solubility atomic/ (0C) (g/cm3) molecular mass Cadmium metal 112.41 320.9 Silver-white, blue-tinged 8.642 Soluble in ammonium nitrate, dilute nitric acid, malleable metal hot sulfuric acid; insoluble in water Cadmium acetate 230.50 256 Colourless

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arsenic, metals, fibres, and dusts IARC Publications Website

almost all cadmium compounds is +2, although a few compounds have been reported in which it is +1. Selected chemical and physical proper-ties of cadmium compounds are presented in the previous IARC Monograph (IARC, 1993a). 1.3 Use of the agents Cadmium metal has specific properties that make it suitable for a wide variety of industrial

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IARC Publications Website Arsenic, Metals, Fibres, and Dusts

Cumulative Cross Index to IARC Monographs. THE MONOGRAPHS. Arsenic and Arsenic Compounds. Beryllium and Beryllium Compounds. Cadmium and Cadmium Compounds. Chromium (VI) Compounds. Nickel and Nickel Compounds. Asbestos (Chrysotile, Amosite, Crocidolite, Tremolite, Actinolite and Anthophyllite) Erionite. Leather Dust

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Cadmium and Cadmium Compounds monographs.iarc

Cadmium and Cadmium Compounds. References to Supplementary Web Tables, Section 2. Elinder CG, Kjellström T, Hogstedt C et al. (1985). Cancer mortality of cadmium workers. Br J Ind Med, 42:651–655. PMID:4041382. Holden H (1980) Further mortality studies on workers exposed to cadmium fume. In: Proceedings of the

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Cadmium and cadmium compounds.

1. IARC Monogr Eval Carcinog Risk Chem Man. 1976;11:39-74. Cadmium and cadmium compounds. [No authors listed] PMID: 186394 [Indexed for MEDLINE]

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The Facts on Cadmium Roadmap on Carcinogens

Cadmium and cadmium compounds are classified as Group 1 carcinogen by the IARC, meaning they are carcinogenic to humans. Cadmium and cadmium compounds cause cancer to the lungs, but associations with cancer of the kidney and the prostate have also been observed.

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eADMIUM AN eADMIUM COMPOUNDS IARC

Table 2. Physical and chemical properties or cadmium and cadmium compounds Chemical name Relative Melting-point Typical physical description Density Solubility atomic/ (0C) (g/cm3) molecular mass Cadmium metal 112.41 320.9 Silver-white, blue-tinged 8.642 Soluble in ammonium nitrate, dilute nitric acid, malleable metal hot sulfuric acid; insoluble in water Cadmium acetate 230.50 256 Colourless

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SCOEL/OPIN/336 cadmium and its inorganic compounds

In exposed workers, inhalation is the main route of exposure. Additional uptake can occur through the consumption of contaminated food and/or tobacco smoking. IARC considers Cd and Cd compounds to be carcinogenic to humans (IARC Group 1), based on sufficient evidence in humans for the carcinogenicity of cadmium and cadmium compounds. Cadmium and cadmium compounds

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Cadmium Compound an overview ScienceDirect Topics

According to the IARC, cadmium and cadmium compounds are classified as class 1 human carcinogens. Besides that, Cd may affect renal function (Kjellstrom et al., 1977). For biological monitoring, blood, and urine cadmium levels are used. Blood cadmium generally reflects current exposure and the levels are usually between 0.2 and 0.8 pg/l (0.0018

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IARC Monographs of Carcinogenic Hazards to Humans and

Cadmium and cadmium compounds. Chromium (VI) compounds. Coal, indoor emissions from household combustion. Coal gasification. Coal-tar pitch. Coke production. Diesel engine exhausts . Gamma-radiation . Haematite mining (underground) Iron and steel founding. MOPP (vincristine -prednisone-nitrogen mustard- procarbazine mixture) Nickel compounds

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3. Studies of Cancer in Experimental Animais The

CADMIUM AN CADMIUM COMPOUNDS 163 the absence of overt toxicity. Starting two weeks later, these diets were fed together with cadmium at 0, 25,50, 100 or 200 (maxmum-tolerated dose) ppm (mglkg diet) as cadmium chloride hemipentahydrate, for 77 weeks, at which time the study was terminated. Histo-

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EXPOSURE TO CADMIUM: A MAJOR PUBLIC HEALTH

International Agency for Research on Cancer (IARC) has classified cadmium and cadmium compounds as . carcinogenic to humans (Group 1), meaning that there is sufficient evidence for their carcinogenicity in humans. 10,11. Risk mitigation recommendations .

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CARCINOGENIC POTENTIAL of CADMIUM in WORKERS

Cadmium and its compounds are also recognised as carcinogenic to humans (Group 1, IARC 1993). The purpose of this document is to summarise the main studies that have examined the carcinogenic potential of cadmium and its compounds in workers.

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Cadmium and its inorganic compounds Wiley Online Library

Cadmium and its inorganic compounds 5 repair, such as the nucleotide excision repair of UV-induced DNA damage (Hartwig et al. 1994), base excision repair after oxidative DNA damage (Dally and Hartwig 1997) and alkylation (Fatur et al. 2003), as well as base mismatch repair (Jin et al. 2003). Cadmium also inhibits isolated repair proteins, i.e. the bacterial formamidopyrimidine-

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Cadmium and its inorganic compounds [MAK Value

Subsequently, in 1993, cadmium and its inorganic compounds were classified by the International Agency for Research on Cancer (IARC 1993) as carcinogenic to humans (IARC Group 1) on the basis of sufficient evidence for an increased relative risk of lung cancer in workers occupationally exposed to cadmium. The following evaluation concentrates

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excerpt on cadmium from Casarett and Doull

and cadmium compounds and human cancer (IARC, 1993). Epi­ demiological studies of cadmium workers found that exposure to various cadmium compounds increased the risk of death from lung cancer (IARC, 1993). Follow-up analysis of some of these cohorts has confirmed that cadmium exposure is associated with elevated

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Cadmium Compounds an overview ScienceDirect Topics

IARC has determined that there is sufficient scientific evidence to classify cadmium and cadmium compounds carcinogenic in humans. In general, Cd compounds are weakly mutagenic in most assay systems ( Filipic and Hei, 2004 ), but have been shown to be

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